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The Iowa State Cyclones (5-2) take on a fellow Big 12 foe when they host the No. 11 BYU Cougars (7-0) on Saturday, October 25, 2025 at Jack Trice Stadium.
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Iowa State vs. BYU Matchup Info
- Game date: Saturday, October 25, 2025
- Game time: 3:30 p.m. ET
- Location: Ames, Iowa
- Venue: Jack Trice Stadium
- TV channel: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Iowa State vs. BYU Odds and Prediction
- Spread favorite: Cyclones (-2.5)
- Moneyline: Cyclones (-136), Cougars (+114)
- Total: 48.5 points
- Pick ATS: BYU (+2.5)
- Pick OU: Under (48.5)
- Prediction: BYU 25, Iowa State 22
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Iowa State vs. BYU Betting Records and Insights
- Iowa State has covered three times in seven games with a spread this season.
- BYU is 5-2-0 ATS this season.
- The Cyclones have covered the spread twice when favored by 2.5 points or more this season (in five opportunities).
- The Cougars have been an underdog by 2.5 points or more once this season, and covered the spread.
- Iowa State games have gone over the point total three out of seven times this season.
- In 2025, three BYU games have hit the over.